Refractoriness medical definition
Webadj. 1. Showing or characterized by obstinate resistance to authority or control: refractory children; refractory behavior. 2. Difficult to melt or work; resistant to heat: a refractory … WebFeb 13, 2024 · However, the definition of refractory, if it includes insufficient response to TPO agents, describes a group with more severe and difficult-to-treat disease. The biology of refractory ITP is largely unexplored and includes oligoclonality, lymphocyte pumps, and other possibilities. ... the mechanism of refractoriness in oligo/monoclonal patients
Refractoriness medical definition
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WebJul 20, 2015 · Definition. Platelet refractoriness can represent a significant clinical problem that complicates provision of platelet transfusions, and which may be associated with … Webplatelet transfusion refractoriness answers are found in the Taber's Medical Dictionary powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web.
WebSep 22, 2016 · An International Working Group (IWG) defined refractory ITP as disease that does not respond to or relapses after splenectomy and that requires treatment to reduce the risk of clinically significant bleeding. 2 The American Society of Hematology ITP Guidelines endorsed this definition as a means of identifying the most severely affected patients. … Webre·frac·to·ry (rĭ-frăk′tə-rē) adj. 1. Showing or characterized by obstinate resistance to authority or control: refractory children; refractory behavior. 2. Difficult to melt or work; resistant to heat: a refractory material such as silica. 3. Resistant to treatment: a refractory case of acne. n. pl. re·frac·to·ries One that is refractory ...
WebApr 12, 2024 · The refractory period is the time after an action potential is generated, during which the excitable cell cannot produce another action potential. There are two subphases of this period, absolute and relative refractoriness. Absolute refractoriness overlaps the depolarization and around 2/3 of repolarization phase.
WebIn conclusion, platelet transfusion refractoriness requires 2 or more inappropriate responses to platelets as defined by below normal PPR or CCI. Platelet transfusion refractoriness is …
WebOct 22, 2024 · The use of allogeneic hematopoietic stem cell transplantation (allo-HSCT) continues to rapidly increase worldwide. 1 However, graft-versus-host disease (GVHD) remains a major limitation of a successful allo-HSCT. 2,3 Up to 50% of patients will develop acute GVHD, despite immunosuppressive prophylaxis, 3-5 and this complication is a … screenshot surface tastenkombinationWebdis·ease (dĭ-zēz′) n. 1. An abnormal condition of a part, organ, or system of an organism resulting from various causes, such as infection, inflammation, environmental factors, or genetic defect, and characterized by an identifiable group of signs, symptoms, or both. 2. A condition or tendency, as of society, regarded as abnormal and harmful. 3 ... screenshot surface tabletWebPlatelet transfusion refractoriness. Platelet transfusion refractoriness is the repeated failure to achieve the desired level of blood platelets in a patient following a platelet transfusion. … paws and whiskers georgiaWebrefractory: See: contumacious , difficult , disobedient , disorderly , fractious , froward , hostile , incorrigible , indomitable , inflexible , insubordinate ... screenshot sur ordiWebRefractoriness. a short-term decrease in the excitability of nervous or muscle tissue occurring immediately after the manifestation of action potential. It can be detected by … paws and whiskers pet groomingWebre·frac·to·ry ( rĕ-frak'tŏr-ē) 1. Resistant to treatment, as of a disease. Synonym (s): intractable (1) , obstinate (2) . 2. Synonym (s): obstinate (1) . [L. refractarius, fr. refringo, pp. -fractus, … screenshot sur ordinateurWebExcitability is inversely related to the charge required for excitation. Excitability of a cardiac cell depends on the passive and active properties of the cell membrane. The passive … paws and whiskers brooklyn mi