Ctgf ligament
WebJun 6, 2014 · Appropriate mechanical loading during occlusion and mastication play an important role in maintaining the homeostasis of periodontal ligament (PDL) tissue. Connective tissue growth factor (CTGF/CCN2), a matricellular protein, is known to upregulate extracellular matrix production, including collagen in PDL tissue. WebOct 5, 2005 · Connective tissue growth factor (CCN2/CTGF) is a cysteine-rich protein with a molecular weight of 36–38 kDa [1–3] and belongs to the CCN family, which stands for C …
Ctgf ligament
Did you know?
WebOct 13, 2024 · Connective tissue growth factor (CTGF) is a cysteine-rich peptide that exhibits platelet-derived growth factor (PDGF)-like biological and immunological … WebThese tissues, including teeth, periodontal ligament, alveolar bones, and dental pulp, present cell types and mechanical properties with great heterogeneity, which is challenging to reproduce in vitro. ... Phase (B) A scaffold area with 600 μm microchannels and PLGA microspheres loaded with CTGF was seeded with hPDLSCs for periodontal ligament ...
WebCCN (for CYR61/ CTGF /NOV) proteins were identified originally from diverse cellular contexts and studied for their growth-promoting activities. It is now known that there are … WebObjectives: To clarify the role of cellular communication network factor 2/connective tissue growth factor (CCN2/CTGF) in periodontal tissue regeneration by investigating, the proliferative and tubulogenic responses of human endothelial cells obtained from the periodontal ligament to CCN2/CTGF.
WebApr 1, 2015 · Connective tissue growth factor (CTGF) is a downstream mediator of TGF-β. This study explores the effects of EMD and TGF-β1 on CTGF in periodontal ligament (PDL) fibroblasts and their interactions in PDL proliferation and development. Methods: Human PDL cells were stimulated with EMD. To explore the effects of EMD and TGF-β1 … WebThe influence of connective tissue growth factor on rabbit ligament injury repair ... Methods: A rabbit ACL injury model was used to study the effect of CTGF on ligament recovery.
WebFeb 12, 2024 · Furthermore, connective tissue growth factor (CTGF) has been shown to promote tendon regeneration via the stimulation of endogenous tendon stem cells. Here, we evaluated the potential of CTGF to promote tenogenic differentiation of ASCs in vitro. Gene and protein expression, cell proliferation, and FAK and ERK1/2 signaling were assessed. ... how do you make trading cardsWebThe impact of CTGF/CTGF+ASC treatment on tendon cell growth and differentiation. (a-d) Changes in relative abundance of genes involved in cell growth and differentiation in flexor tendons 14 days ... phone for fox newsWebFull length CTGF can be proteolytically cleaved in certain tissues to yield N-terminal truncated isoforms, which, depending on the isoform, contain only the TSP type I and … how do you make treated lumberWebNational Center for Biotechnology Information how do you make trades in my career nba 2k16WebJul 29, 2024 · The current study showed that CTGF could promote the recovery of an injured anterior cruciate ligament. It can upregulate mRNA and expression of TGF-β1, COL1, COL2, SOX9, and tissue inhibitor of TIMP-1, and downregulate mRNA and expression of MMP-13, suggesting that the curative effect of CTGF on injured rabbit ligaments is … phone for frontier communicationsWebJun 3, 2011 · Abstract. Highlights: {yields} CCN2/CTGF localizes to the ligament-to-bone interface, but is not to the midsubstance region of human anterior cruciate ligament (ACL). {yields} Mechanical stretch induces higher increase of CCN2/CTGF gene expression and protein secretion in ACL interface cells compared with ACL midsubstance cells. {yields} … how do you make trifleWebSep 17, 2024 · Cell–cell communication is an essential process to respond to biological stimuli and sustain the micro environmental homeostasis of human periodontal ligament stem cells (hPDLSCs). Connective tissue growth factor (CTGF), a critical secreted matrix protein, exhibits significant tasks in regulating the cell-cell and cell-matrix interactions. phone for emergency use only